Some users may encounter issues attempting to install or uninstall Plex Media Server on Windows. Errors could also occur when trying to upgrade an existing installation. In many cases, this will manifest as a 0x80070643 error message, though other errors can also occur.
Warning: These types of issues occur most commonly when also using tools such as “registry optimizers” or third-party “uninstaller” tools (such as CCleaner or Revo Uninstaller). We generally recommend not using these types of tools, as the unintended issues they cause often end up outweighing any actual benefit they bring.
Don’t Remove Package Cache Install Files
As a general note, you should not remove package cache installer files related to Plex Media Server. If you do so, you’ll have trouble uninstalling or upgrading installations. Those files are found under:
C:\ProgramData\Package Cache…as well as:
C:\Windows\InstallerLeave the content there alone to avoid issues.
Resolving Issues
Typically, the first and safest thing to do is to run Microsoft’s “Fix It” tool, when encountering errors trying to install, uninstall, or upgrade on a Windows computer (such as an error that a .msi file is missing). In the vast majority of cases, running the “Fix It” will resolve the issue. Instructions are in the Microsoft article linked below.
Related Page: Microsoft: Fix problems that programs cannot be installed or uninstalled
Tip!: Additional information about running the “Fix It” tools is available in our forums. This includes details on determining which particular package cannot be found for uninstalling.
Other times, problems may be caused by the same issues that can prevent Windows Update from working correctly.
Related Page: Microsoft KB: Fix Windows Update issues